購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗PHF21A多克隆抗體
英文名稱(chēng)： Anti-PHF21A rabbit polyclonal antibody
別 名： PHD finger protein 21A; BHC80; BM-006
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PHF21A
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
PHF21A |
|
Immunogen: |
Fusion protein of human PHF21A |
|
Full name: |
PHD finger protein 21A |
|
Synonyms: |
BHC80; BM-006 |
|
SwissProt: |
Q96BD5 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human colorectal cancer and human ovarian cancer |
|
IHC Recommend dilution: |
40-200 |
