小鼠抗FBLIM1單克隆抗體

Background:

This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul

Applications:

WB

Name of antibody:

FBLIM1

Immunogen:

Fusion protein of human FBLIM1

Full name:

filamin binding LIM protein 1 (FBLIM1), transcript variant 1

Synonyms:

CAL; FBLP-1; FBLP1

SwissProt:

Q8WUP2

WB Predicted band size:

41 kDa

WB Positive control:

HepG2, SVT2 cell lysates

WB Recommended dilution:

200-1000